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JAMA Internal Medicine

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Levels of Evidence Needed for Changing Indications, Contraindications, and Food and Drug Administration Labeling: The Case of Metformin—Reply
Ronan Roussel, MD, PhD, Deepak L. Bhatt, MD, MPH, Philippe Gabriel Steg, MD, Reduction of Atherothrombosis for Continued  Health (REACH) Registry Investigators
Arch Intern Med. 2011;171(11):1042-1043.
Published online June 13, 2011

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