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Levels of Evidence Needed for Changing Indications, Contraindications, and Food and Drug Administration Labeling: The Case of Metformin
Dean T. Eurich, BSP, PhD, Sumit R. Majumdar, MD, MPH, Finlay A. McAlister, MD, MSc, Ross T. Tsuyuki, BSc(Pharm), PharmD, MSc, Jeffrey A. Johnson, PhD
Arch Intern Med. 2011;171(11):1042-1043.
Published online June 13, 2011

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